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Implication of the F-Box Protein FBXL21 in Circadian Pacemaker Function in Mammals
In mammals, the circadian clock relies on interlocked feedback loops involving clock genes and their protein products. Post-translational modifications control intracellular trafficking, functionality and degradation of clock proteins and are keys to the functioning of the clock as recently exemplif...
Autores principales: | Dardente, Hugues, Mendoza, Jorge, Fustin, Jean-Michel, Challet, Etienne, Hazlerigg, David G. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2568807/ https://www.ncbi.nlm.nih.gov/pubmed/18953409 http://dx.doi.org/10.1371/journal.pone.0003530 |
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