Cdx1 and c-Myc Foster the Initiation of Transdifferentiation of the Normal Esophageal Squamous Epithelium toward Barrett's Esophagus

BACKGROUND: Barrett's esophagus is a premalignant condition whereby the normal stratified squamous esophageal epithelium undergoes a transdifferentiation program resulting in a simple columnar epithelium reminiscent of the small intestine. These changes are typically associated with the stratif...

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Detalles Bibliográficos
Autores principales: Stairs, Douglas B., Nakagawa, Hiroshi, Klein-Szanto, Andres, Mitchell, Shukriyyah D., Silberg, Debra G., Tobias, John W., Lynch, John P., Rustgi, Anil K.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2568822/
https://www.ncbi.nlm.nih.gov/pubmed/18953412
http://dx.doi.org/10.1371/journal.pone.0003534

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2568822/
https://www.ncbi.nlm.nih.gov/pubmed/18953412
http://dx.doi.org/10.1371/journal.pone.0003534

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