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Role of αBI5 and αBT162 residues in subunit interaction during oligomerization of αB-crystallin

PURPOSE: To determine whether the residues in the NH(2)- and COOH-terminal extensions interact with one another during oligomerization of αB-crystallin. METHODS: Site-directed mutagenesis was used to mutate αBI5 and αBT162 residues to Cys. The recombinant I5C and T162C proteins were expressed in Esc...

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Detalles Bibliográficos
Autores principales: Murugesan, Raju, Santhoshkumar, Puttur, Sharma, K. Krishna
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2568893/
https://www.ncbi.nlm.nih.gov/pubmed/18941542