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Role of αBI5 and αBT162 residues in subunit interaction during oligomerization of αB-crystallin
PURPOSE: To determine whether the residues in the NH(2)- and COOH-terminal extensions interact with one another during oligomerization of αB-crystallin. METHODS: Site-directed mutagenesis was used to mutate αBI5 and αBT162 residues to Cys. The recombinant I5C and T162C proteins were expressed in Esc...
Autores principales: | Murugesan, Raju, Santhoshkumar, Puttur, Sharma, K. Krishna |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Molecular Vision
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2568893/ https://www.ncbi.nlm.nih.gov/pubmed/18941542 |
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