Identification and Functional Characterization of an N-terminal Oligomerization Domain for Polycystin-2

Autosomal dominant polycystic kidney disease (ADPKD), the most common inherited cause of kidney failure, is caused by mutations in either PKD1 (85%) or PKD2 (15%). The PKD2 protein, polycystin-2 (PC2 or TRPP2), is a member of the transient receptor potential (TRP) superfamily and functions as a non-...

Descripción completa

Detalles Bibliográficos
Autores principales: Feng, Shuang, Okenka, Genevieve M., Bai, Chang-Xi, Streets, Andrew J., Newby, Linda J., DeChant, Brett T., Tsiokas, Leonidas, Obara, Tomoko, Ong, Albert C. M.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2008
Materias:
Molecular Basis of Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2568912/
https://www.ncbi.nlm.nih.gov/pubmed/18701462
http://dx.doi.org/10.1074/jbc.M803834200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2568912/
https://www.ncbi.nlm.nih.gov/pubmed/18701462
http://dx.doi.org/10.1074/jbc.M803834200

Ejemplares similares