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Time-resolved Mechanism of Extracellular Gate Opening and Substrate Binding in a Glutamate Transporter

Glutamate transporters, also referred to as excitatory amino acid transporters (EAATs), are membrane proteins that regulate glutamatergic signal transmission by clearing excess glutamate after its release at synapses. A structure-based understanding of their molecular mechanisms of function has been...

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Detalles Bibliográficos
Autores principales: Shrivastava, Indira H., Jiang, Jie, Amara, Susan G., Bahar, Ivet
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2568915/
https://www.ncbi.nlm.nih.gov/pubmed/18678877
http://dx.doi.org/10.1074/jbc.M800889200