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Stat1 Phosphorylation Determines Ras Oncogenicity by Regulating p27(Kip1)
Inactivation of p27(Kip1) is implicated in tumorigenesis and has both prognostic and treatment-predictive values for many types of human cancer. The transcription factor Stat1 is essential for innate immunity and tumor immunosurveillance through its ability to act downstream of interferons. Herein,...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2568943/ https://www.ncbi.nlm.nih.gov/pubmed/18941537 http://dx.doi.org/10.1371/journal.pone.0003476 |