Genetic Association and Expression Studies Indicate a Role of Toll-Like Receptor 8 in Pulmonary Tuberculosis

Despite high rates of exposure, only 5–10% of people infected with Mycobacterium tuberculosis will develop active tuberculosis (TB) disease, suggesting a significant role for genetic variation in the human immune response to this infection. Here, we studied TB association and expression of 18 genes...

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Detalles Bibliográficos
Autores principales: Davila, Sonia, Hibberd, Martin L., Hari Dass, Ranjeeta, Wong, Hazel E. E., Sahiratmadja, Edhyana, Bonnard, Carine, Alisjahbana, Bachti, Szeszko, Jeffrey S., Balabanova, Yanina, Drobniewski, Francis, van Crevel, Reinout, van de Vosse, Esther, Nejentsev, Sergey, Ottenhoff, Tom H. M., Seielstad, Mark
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2568981/
https://www.ncbi.nlm.nih.gov/pubmed/18927625
http://dx.doi.org/10.1371/journal.pgen.1000218

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2568981/
https://www.ncbi.nlm.nih.gov/pubmed/18927625
http://dx.doi.org/10.1371/journal.pgen.1000218

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