Differential regulation of morphine antinociceptive effects by endogenous enkephalinergic system in the forebrain of mice

BACKGROUND: Mice lacking the preproenkephalin (ppENK) gene are hyperalgesic and show more anxiety and aggression than wild-type (WT) mice. The marked behavioral changes in ppENK knock-out (KO) mice appeared to occur in supraspinal response to painful stimuli. However the functional role of enkephali...

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Detalles Bibliográficos
Autores principales: Chen, Tsung-Chieh, Cheng, Ying-Ying, Sun, Wei-Zen, Shyu, Bai-Chuang
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2569012/
https://www.ncbi.nlm.nih.gov/pubmed/18826595
http://dx.doi.org/10.1186/1744-8069-4-41

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2569012/
https://www.ncbi.nlm.nih.gov/pubmed/18826595
http://dx.doi.org/10.1186/1744-8069-4-41

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