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Preclinical evaluation of dasatinib, a potent Src kinase inhibitor, in melanoma cell lines

BACKGROUND: Metastatic melanoma is a highly chemotherapy resistant tumour. The use of newer targeted therapies alone and in combination with chemotherapy may offer new hope of improving response to treatment. Dasatinib, a multi-target kinase inhibitor, is currently approved for the treatment of chro...

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Detalles Bibliográficos
Autores principales: Eustace, Alex J, Crown, John, Clynes, Martin, O'Donovan, Norma
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2569026/
https://www.ncbi.nlm.nih.gov/pubmed/18823558
http://dx.doi.org/10.1186/1479-5876-6-53