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SH(2)-Inositol Phosphatase 1 Negatively Influences Early Megakaryocyte Progenitors

BACKGROUND: The SH2-containing-5′inositol phosphatase-1 (SHIP) influences signals downstream of cytokine/chemokine receptors that play a role in megakaryocytopoiesis, including thrombopoietin, stromal-cell-derived-Factor-1/CXCL-12 and interleukin-3. We hypothesize that SHIP might control megakaryocy...

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Detalles Bibliográficos
Autores principales: Perez, Lia E., Desponts, Caroline, Parquet, Nancy, Kerr, William G.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2569203/
https://www.ncbi.nlm.nih.gov/pubmed/18958162
http://dx.doi.org/10.1371/journal.pone.0003565