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Anthrax Edema Toxin Modulates PKA- and CREB-Dependent Signaling in Two Phases
BACKGROUND: Anthrax edema toxin (EdTx) is an adenylate cyclase which operates in the perinuclear region of host cells. However, the action of EdTx is poorly understood, especially at molecular level. The ability of EdTx to modulate cAMP-dependent signaling was studied in Jurkat T cells and was compa...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2569206/ https://www.ncbi.nlm.nih.gov/pubmed/18958164 http://dx.doi.org/10.1371/journal.pone.0003564 |