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Anthrax Edema Toxin Modulates PKA- and CREB-Dependent Signaling in Two Phases

BACKGROUND: Anthrax edema toxin (EdTx) is an adenylate cyclase which operates in the perinuclear region of host cells. However, the action of EdTx is poorly understood, especially at molecular level. The ability of EdTx to modulate cAMP-dependent signaling was studied in Jurkat T cells and was compa...

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Detalles Bibliográficos
Autores principales: Puhar, Andrea, Dal Molin, Federica, Horvath, Stéphanie, Ladants, Daniel, Montecucco, Cesare
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2569206/
https://www.ncbi.nlm.nih.gov/pubmed/18958164
http://dx.doi.org/10.1371/journal.pone.0003564