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Analyses and Comparison of Accuracy of Different Genotype Imputation Methods

The power of genetic association analyses is often compromised by missing genotypic data which contributes to lack of significant findings, e.g., in in silico replication studies. One solution is to impute untyped SNPs from typed flanking markers, based on known linkage disequilibrium (LD) relations...

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Detalles Bibliográficos
Autores principales: Pei, Yu-Fang, Li, Jian, Zhang, Lei, Papasian, Christopher J., Deng, Hong-Wen
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2569208/
https://www.ncbi.nlm.nih.gov/pubmed/18958166
http://dx.doi.org/10.1371/journal.pone.0003551