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Analyses and Comparison of Accuracy of Different Genotype Imputation Methods
The power of genetic association analyses is often compromised by missing genotypic data which contributes to lack of significant findings, e.g., in in silico replication studies. One solution is to impute untyped SNPs from typed flanking markers, based on known linkage disequilibrium (LD) relations...
Autores principales: | Pei, Yu-Fang, Li, Jian, Zhang, Lei, Papasian, Christopher J., Deng, Hong-Wen |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2569208/ https://www.ncbi.nlm.nih.gov/pubmed/18958166 http://dx.doi.org/10.1371/journal.pone.0003551 |
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