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Recruitment of the Complete hTREX Complex Is Required for Kaposi's Sarcoma–Associated Herpesvirus Intronless mRNA Nuclear Export and Virus Replication

A cellular pre-mRNA undergoes various post-transcriptional processing events, including capping, splicing and polyadenylation prior to nuclear export. Splicing is particularly important for mRNA nuclear export as two distinct multi-protein complexes, known as human TREX (hTREX) and the exon-junction...

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Detalles Bibliográficos
Autores principales: Boyne, James R., Colgan, Kevin J., Whitehouse, Adrian
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2569588/
https://www.ncbi.nlm.nih.gov/pubmed/18974867
http://dx.doi.org/10.1371/journal.ppat.1000194