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Discovery of frameshifting in Alphavirus 6K resolves a 20-year enigma

BACKGROUND: The genus Alphavirus includes several potentially lethal human viruses. Additionally, species such as Sindbis virus and Semliki Forest virus are important vectors for gene therapy, vaccination and cancer research, and important models for virion assembly and structural analyses. The geno...

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Detalles Bibliográficos
Autores principales: Firth, Andrew E, Chung, Betty YW, Fleeton, Marina N, Atkins, John F
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2569925/
https://www.ncbi.nlm.nih.gov/pubmed/18822126
http://dx.doi.org/10.1186/1743-422X-5-108