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Evaluation of human gene variant detection in amplicon pools by the GS-FLX parallel Pyrosequencer
BACKGROUND: A new priority in genome research is large-scale resequencing of genes to understand the molecular basis of hereditary disease and cancer. We assessed the ability of massively parallel pyrosequencing to identify sequence variants in pools. From a large collection of human PCR samples we...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2569949/ https://www.ncbi.nlm.nih.gov/pubmed/18842124 http://dx.doi.org/10.1186/1471-2164-9-464 |