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Comprehensive study of proteasome inhibitors against Plasmodium falciparum laboratory strains and field isolates from Gabon

BACKGROUND: The emergence and spread of Plasmodium falciparum resistance to almost all available antimalarial drugs necessitates the search for new chemotherapeutic compounds. The ubiquitin/proteasome system plays a major role in overall protein turnover, especially in fast dividing eukaryotic cells...

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Detalles Bibliográficos
Autores principales: Kreidenweiss, Andrea, Kremsner, Peter G, Mordmüller, Benjamin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2569964/
https://www.ncbi.nlm.nih.gov/pubmed/18816382
http://dx.doi.org/10.1186/1475-2875-7-187