Synaptotagmin arrests the SNARE complex before triggering fast, efficient membrane fusion in response to Ca(2+)

Neuronal communication is mediated by Ca(2+)-triggered fusion of transmitter-filled synaptic vesicles with the presynaptic plasma membrane. Synaptotagmin I functions as a Ca(2+) sensor that regulates exocytosis, whereas soluble N-ethylmaleimide–sensitive factor attachment protein (SNAP) receptor (SN...

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Detalles Bibliográficos
Autores principales: Chicka, Michael C, Hui, Enfu, Liu, Huisheng, Chapman, Edwin R
Formato: Texto
Lenguaje:English
Publicado: 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570314/
https://www.ncbi.nlm.nih.gov/pubmed/18622390
http://dx.doi.org/10.1038/nsmb.1463

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570314/
https://www.ncbi.nlm.nih.gov/pubmed/18622390
http://dx.doi.org/10.1038/nsmb.1463

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