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Synaptotagmin arrests the SNARE complex before triggering fast, efficient membrane fusion in response to Ca(2+)
Neuronal communication is mediated by Ca(2+)-triggered fusion of transmitter-filled synaptic vesicles with the presynaptic plasma membrane. Synaptotagmin I functions as a Ca(2+) sensor that regulates exocytosis, whereas soluble N-ethylmaleimide–sensitive factor attachment protein (SNAP) receptor (SN...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570314/ https://www.ncbi.nlm.nih.gov/pubmed/18622390 http://dx.doi.org/10.1038/nsmb.1463 |