Forkhead Transcription Factors (FoxOs) Promote Apoptosis of Insulin-Resistant Macrophages During Cholesterol-Induced Endoplasmic Reticulum Stress

OBJECTIVE—Endoplasmic reticulum stress increases macrophage apoptosis, contributing to the complications of atherosclerosis. Insulin-resistant macrophages are more susceptible to endoplasmic reticulum stress–associated apoptosis probably contributing to macrophage death and necrotic core formation i...

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Detalles Bibliográficos
Autores principales: Senokuchi, Takafumi, Liang, Chien-Ping, Seimon, Tracie A., Han, Seongah, Matsumoto, Michihiro, Banks, Alexander S., Paik, Ji-Hye, DePinho, Ronald A., Accili, Domenico, Tabas, Ira, Tall, Alan R.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2008
Materias:
Signal Transduction
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570393/
https://www.ncbi.nlm.nih.gov/pubmed/18728232
http://dx.doi.org/10.2337/db08-0520

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570393/
https://www.ncbi.nlm.nih.gov/pubmed/18728232
http://dx.doi.org/10.2337/db08-0520

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