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Forkhead Transcription Factors (FoxOs) Promote Apoptosis of Insulin-Resistant Macrophages During Cholesterol-Induced Endoplasmic Reticulum Stress

OBJECTIVE—Endoplasmic reticulum stress increases macrophage apoptosis, contributing to the complications of atherosclerosis. Insulin-resistant macrophages are more susceptible to endoplasmic reticulum stress–associated apoptosis probably contributing to macrophage death and necrotic core formation i...

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Detalles Bibliográficos
Autores principales:	Senokuchi, Takafumi, Liang, Chien-Ping, Seimon, Tracie A., Han, Seongah, Matsumoto, Michihiro, Banks, Alexander S., Paik, Ji-Hye, DePinho, Ronald A., Accili, Domenico, Tabas, Ira, Tall, Alan R.
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2008
Materias:	Signal Transduction
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570393/ https://www.ncbi.nlm.nih.gov/pubmed/18728232 http://dx.doi.org/10.2337/db08-0520

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