Peripheral, but Not Central, CB1 Antagonism Provides Food Intake–Independent Metabolic Benefits in Diet-Induced Obese Rats

OBJECTIVE—Blockade of the CB1 receptor is one of the promising strategies for the treatment of obesity. Although antagonists suppress food intake and reduce body weight, the role of central versus peripheral CB1 activation on weight loss and related metabolic parameters remains to be elucidated. We...

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Detalles Bibliográficos
Autores principales: Nogueiras, Ruben, Veyrat-Durebex, Christelle, Suchanek, Paula M., Klein, Marcella, Tschöp, Johannes, Caldwell, Charles, Woods, Stephen C., Wittmann, Gabor, Watanabe, Masahiko, Liposits, Zsolt, Fekete, Csaba, Reizes, Ofer, Rohner-Jeanrenaud, Francoise, Tschöp, Matthias H.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2008
Materias:
Obesity Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570394/
https://www.ncbi.nlm.nih.gov/pubmed/18716045
http://dx.doi.org/10.2337/db08-0161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570394/
https://www.ncbi.nlm.nih.gov/pubmed/18716045
http://dx.doi.org/10.2337/db08-0161

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