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Assessing the Combined Impact of 18 Common Genetic Variants of Modest Effect Sizes on Type 2 Diabetes Risk

OBJECTIVES—Genome-wide association studies have dramatically increased the number of common genetic variants that are robustly associated with type 2 diabetes. A possible clinical use of this information is to identify individuals at high risk of developing the disease, so that preventative measures...

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Detalles Bibliográficos
Autores principales: Lango, Hana, Palmer, Colin N.A., Morris, Andrew D., Zeggini, Eleftheria, Hattersley, Andrew T., McCarthy, Mark I., Frayling, Timothy M., Weedon, Michael N.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570411/
https://www.ncbi.nlm.nih.gov/pubmed/18591388
http://dx.doi.org/10.2337/db08-0504