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NET1-mediated RhoA activation facilitates lysophosphatidic acid-induced cell migration and invasion in gastric cancer

The most lethal aspects of gastric adenocarcinoma (GA) are its invasive and metastatic properties. This aggressive phenotype remains poorly understood. We have recently identified neuroepithelial cell transforming gene 1 (NET1), a guanine exchange factor (GEF), as a novel GA-associated gene. Neuroep...

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Detalles Bibliográficos
Autores principales: Murray, D, Horgan, G, MacMathuna, P, Doran, P
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570507/
https://www.ncbi.nlm.nih.gov/pubmed/18827818
http://dx.doi.org/10.1038/sj.bjc.6604688