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In vitro phosphorylation of BRCA2 by the checkpoint kinase CHEK2
Germline mutations in both BRCA2 and CHEK2 are associated with an increased risk for male breast cancer. To search for potential interactions between the products of these breast cancer susceptibility genes, we undertook systematic mapping of BRCA2 for potential phosphorylation sites by CHEK2. In vi...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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Nature Publishing Group
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570522/ https://www.ncbi.nlm.nih.gov/pubmed/18797466 http://dx.doi.org/10.1038/sj.bjc.6604644 |