A novel AKT3 mutation in melanoma tumours and cell lines

Recently, a rare activating mutation of AKT1 (E17K) has been reported in breast, ovarian, and colorectal cancers. However, analogous activating mutations in AKT2 or AKT3 have not been identified in any cancer lineage. To determine the prevalence of AKT E17K mutations in melanoma, the most aggressive...

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Detalles Bibliográficos
Autores principales: Davies, M A, Stemke-Hale, K, Tellez, C, Calderone, T L, Deng, W, Prieto, V G, Lazar, A J F, Gershenwald, J E, Mills, G B
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570525/
https://www.ncbi.nlm.nih.gov/pubmed/18813315
http://dx.doi.org/10.1038/sj.bjc.6604637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570525/
https://www.ncbi.nlm.nih.gov/pubmed/18813315
http://dx.doi.org/10.1038/sj.bjc.6604637

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