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Histidine Residues at the Active Site of the Pasteurella multocida Toxin

We have investigated histidine residues near the active site of the mitogenic Pasteurella multocida toxin. Mutation of H1202 or H1228 had little effect, while the effect of mutation on H1223 depended on the amino acid substituted. Mutation of H1205 caused complete loss of activity, indicating its im...

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Detalles Bibliográficos
Autores principales: Pullinger, Gillian D, Lax, Alistair J
Formato: Texto
Lenguaje:English
Publicado: Bentham Science Publishers Ltd. 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570546/
https://www.ncbi.nlm.nih.gov/pubmed/18949067
http://dx.doi.org/10.2174/1874091X00701010007