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Predicting In Vivo Efficacy of Potential Restenosis Therapies by Cell Culture Studies: Species-Dependent Susceptibility of Vascular Smooth Muscle Cells

Although drug-eluting stents (DES) are successfully utilized for restenosis therapy, the development of local and systemic therapeutic means including nanoparticles (NP) continues. Lack of correlation between in vitro and in vivo studies is one of the major drawbacks in developing new drug delivery...

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Detalles Bibliográficos
Autores principales: Hila, Epstein, Rabinovich, Laura, Banai, Shmuel, Elazar, Vicktoria, Gao, Jianchuan, Chorny, Michael, Danenebrg, Haim D, Golomb, Gershon
Formato: Texto
Lenguaje:English
Publicado: Bentham Open 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570571/
https://www.ncbi.nlm.nih.gov/pubmed/18949101
http://dx.doi.org/10.2174/1874192400802010060