Mutation of the Zebrafish Nucleoporin elys Sensitizes Tissue Progenitors to Replication Stress

The recessive lethal mutation flotte lotte (flo) disrupts development of the zebrafish digestive system and other tissues. We show that flo encodes the ortholog of Mel-28/Elys, a highly conserved gene that has been shown to be required for nuclear integrity in worms and nuclear pore complex (NPC) as...

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Detalles Bibliográficos
Autores principales: Davuluri, Gangarao, Gong, Weilong, Yusuff, Shamila, Lorent, Kristin, Muthumani, Manimegalai, Dolan, Amy C., Pack, Michael
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570612/
https://www.ncbi.nlm.nih.gov/pubmed/18974873
http://dx.doi.org/10.1371/journal.pgen.1000240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570612/
https://www.ncbi.nlm.nih.gov/pubmed/18974873
http://dx.doi.org/10.1371/journal.pgen.1000240

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