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Sp1 is involved in H(2)O(2)-induced PUMA gene expression and apoptosis in colorectal cancer cells

BACKGROUND: Reactive oxygen species (ROS) are intricately involved in tumor progression through effects on proliferation, apoptosis and metastasis. But how ROS works is not well understood. In previous study, we found PUMA (p53-upregulated modulator of apoptosis) played an important role in oxalipla...

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Detalles Bibliográficos
Autores principales: Wang, Xinying, Wang, Jing, Lin, Shiyong, Geng, Yan, Wang, Jide, Jiang, Bo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570657/
https://www.ncbi.nlm.nih.gov/pubmed/18811981
http://dx.doi.org/10.1186/1756-9966-27-44