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Exact model reduction of combinatorial reaction networks

BACKGROUND: Receptors and scaffold proteins usually possess a high number of distinct binding domains inducing the formation of large multiprotein signaling complexes. Due to combinatorial reasons the number of distinguishable species grows exponentially with the number of binding domains and can ea...

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Detalles Bibliográficos
Autores principales: Conzelmann, Holger, Fey, Dirk, Gilles, Ernst D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570670/
https://www.ncbi.nlm.nih.gov/pubmed/18755034
http://dx.doi.org/10.1186/1752-0509-2-78