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Proteomic Profiling of Plasmodium Sporozoite Maturation Identifies New Proteins Essential for Parasite Development and Infectivity

Plasmodium falciparum sporozoites that develop and mature inside an Anopheles mosquito initiate a malaria infection in humans. Here we report the first proteomic comparison of different parasite stages from the mosquito—early and late oocysts containing midgut sporozoites, and the mature, infectious...

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Detalles Bibliográficos
Autores principales: Lasonder, Edwin, Janse, Chris J., van Gemert, Geert-Jan, Mair, Gunnar R., Vermunt, Adriaan M. W., Douradinha, Bruno G., van Noort, Vera, Huynen, Martijn A., Luty, Adrian J. F., Kroeze, Hans, Khan, Shahid M., Sauerwein, Robert W., Waters, Andrew P., Mann, Matthias, Stunnenberg, Hendrik G.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570797/
https://www.ncbi.nlm.nih.gov/pubmed/18974882
http://dx.doi.org/10.1371/journal.ppat.1000195