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Beta Cells within Single Human Islets Originate from Multiple Progenitors

BACKGROUND: In both humans and rodents, glucose homeostasis is controlled by micro-organs called islets of Langerhans composed of beta cells, associated with other endocrine cell types. Most of our understanding of islet cell differentiation and morphogenesis is derived from rodent developmental stu...

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Detalles Bibliográficos
Autores principales: Scharfmann, Raphaël, Xiao, Xiangwei, Heimberg, Harry, Mallet, Jacques, Ravassard, Philippe
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2571119/
https://www.ncbi.nlm.nih.gov/pubmed/18958289
http://dx.doi.org/10.1371/journal.pone.0003559