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The Death Receptor 3–TNF-like protein 1A pathway drives adverse bone pathology in inflammatory arthritis

Rheumatoid arthritis (RA) is a chronic inflammatory disease of synovial joints that is associated with cartilage and bone destruction. Death Receptor 3 (DR3), a tumor necrosis factor (TNF) receptor superfamily member, has recently been associated with the pathogenesis of RA. We demonstrate that abse...

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Detalles Bibliográficos
Autores principales: Bull, Melanie Jane, Williams, Anwen Siân, Mecklenburgh, Zarabeth, Calder, Claudia Jane, Twohig, Jason Peter, Elford, Carole, Evans, Bronwen Alice James, Rowley, Tania F., Slebioda, Tomasz J., Taraban, Vadim Y., Al-Shamkhani, Aymen, Wang, Eddie Chung Yern
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2571920/
https://www.ncbi.nlm.nih.gov/pubmed/18824582
http://dx.doi.org/10.1084/jem.20072378