Blockade of tumor necrosis factor in collagen-induced arthritis reveals a novel immunoregulatory pathway for Th1 and Th17 cells

IL-17 is implicated in the pathogenesis of rheumatoid arthritis (RA) and has previously been shown to be induced by tumor necrosis factor (TNF) in vitro. The aim of this study was to assess the impact of TNF inhibition on IL-17 production in collagen-induced arthritis, a model of RA. TNF blockade us...

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Detalles Bibliográficos
Autores principales: Notley, Clare A., Inglis, Julia J., Alzabin, Saba, McCann, Fiona E., McNamee, Kay E., Williams, Richard O.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Brief Definitive Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2571924/
https://www.ncbi.nlm.nih.gov/pubmed/18936235
http://dx.doi.org/10.1084/jem.20072707

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2571924/
https://www.ncbi.nlm.nih.gov/pubmed/18936235
http://dx.doi.org/10.1084/jem.20072707

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