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Mind bomb 1 in the lymphopoietic niches is essential for T and marginal zone B cell development

Notch signaling regulates lineage decisions at multiple stages of lymphocyte development, and Notch activation requires the endocytosis of Notch ligands in the signal-sending cells. Four E3 ubiquitin ligases, Mind bomb (Mib) 1, Mib2, Neuralized (Neur) 1, and Neur2, regulate the Notch ligands to acti...

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Detalles Bibliográficos
Autores principales: Song, Ran, Kim, Young-Woong, Koo, Bon-Kyoung, Jeong, Hyun-Woo, Yoon, Mi-Jeong, Yoon, Ki-Jun, Jun, Dong-Jae, Im, Sun-Kyoung, Shin, Juhee, Kong, Myoung-Phil, Kim, Kyong-Tai, Yoon, Keejung, Kong, Young-Yun
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2571928/
https://www.ncbi.nlm.nih.gov/pubmed/18824586
http://dx.doi.org/10.1084/jem.20081344