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TLR3 is an endogenous sensor of tissue necrosis during acute inflammatory events
Ligands from dying cells are a source of Toll-like receptor (TLR) activating agents. Although TLR3 is known to respond to RNA from necrotic cells, the relative importance of this response in vivo during acute inflammatory processes has not been fully explored. We observed the involvement of TLR3 act...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2571935/ https://www.ncbi.nlm.nih.gov/pubmed/18838547 http://dx.doi.org/10.1084/jem.20081370 |