Cargando…

TLR3 is an endogenous sensor of tissue necrosis during acute inflammatory events

Ligands from dying cells are a source of Toll-like receptor (TLR) activating agents. Although TLR3 is known to respond to RNA from necrotic cells, the relative importance of this response in vivo during acute inflammatory processes has not been fully explored. We observed the involvement of TLR3 act...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cavassani, Karen A., Ishii, Makoto, Wen, Haitao, Schaller, Matthew A., Lincoln, Pamela M., Lukacs, Nicholas W., Hogaboam, Cory M., Kunkel, Steven L.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2008
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2571935/ https://www.ncbi.nlm.nih.gov/pubmed/18838547 http://dx.doi.org/10.1084/jem.20081370

Ejemplares similares

The Critical Role of Notch Ligand Delta-like 1 in the Pathogenesis of Influenza A Virus (H1N1) Infection
por: Ito, Toshihiro, et al.
Publicado: (2011)

Respiratory viral infections drive chemokine expression and exacerbate the asthmatic response
por: Schaller, Matthew, et al.
Publicado: (2006)

Delta-Like 4 Differentially Regulates Murine CD4(+) T Cell Expansion via BMI1
por: Schaller, Matthew A., et al.
Publicado: (2010)

Chemokines and their role in airway hyper-reactivity
por: Blease, Kate, et al.
Publicado: (2000)

Toll Like Receptor 3 Plays a Critical Role in the Progression and Severity of Acetaminophen-Induced Hepatotoxicity
por: Cavassani, Karen A., et al.
Publicado: (2013)

Neonatal monocytes exhibit a unique histone modification landscape
por: Bermick, Jennifer R., et al.
Publicado: (2016)

Pivotal Role of Signal Transducer and Activator of Transcription (Stat)4 and Stat6 in the Innate Immune Response during Sepsis
por: Matsukawa, Akihiro, et al.
Publicado: (2001)

Epigenetic control of Foxp3 by SMYD3 H3K4 histone methyltransferase controls iTreg development and regulates pathogenic T cell responses during pulmonary viral infection
por: de Almeida Nagata, Denise E., et al.
Publicado: (2015)

Cytokine Induced Phenotypic and Epigenetic Signatures Are Key to Establishing Specific Macrophage Phenotypes
por: Kittan, Nicolai A., et al.
Publicado: (2013)

Dysregulated Cytokine Expression by CD4+ T cells from Post-Septic Mice Modulates both Th1 and Th2-Mediated Granulomatous Lung Inflammation
por: Carson, William F., et al.
Publicado: (2011)

Senescent stromal cell-induced divergence and therapeutic resistance in T cell acute lymphoblastic leukemia/lymphoma
por: Habiel, David M., et al.
Publicado: (2016)

MHV68 Latency Modulates the Host Immune Response to Influenza A Virus
por: Saito, Fumitake, et al.
Publicado: (2013)

TRAIL-Dependent Resolution of Pulmonary Fibrosis
por: Habiel, David M., et al.
Publicado: (2018)

Notch ligand Delta-like 4 regulates disease pathogenesis during respiratory viral infections by modulating Th2 cytokines
por: Schaller, Matthew A., et al.
Publicado: (2007)

Circulating monocytes from prostate cancer patients promote invasion and motility of epithelial cells
por: Cavassani, Karen A., et al.
Publicado: (2018)

Elevated Notch ligands in serum are associated with HIV/TB coinfection
por: Bermick, Jennifer R., et al.
Publicado: (2021)

Identification of Key Processes that Control Tumor Necrosis Factor Availability in a Tuberculosis Granuloma
por: Fallahi-Sichani, Mohammad, et al.
Publicado: (2010)

TLR9-induced interferon β is associated with protection from gammaherpesvirus-induced exacerbation of lung fibrosis
por: Luckhardt, Tracy R, et al.
Publicado: (2011)

Endogenous Reverse Transcriptase Inhibition Attenuates TLR5-Mediated Inflammation
por: Dopkins, Nicholas, et al.
Publicado: (2023)

Heterogeneity in fibroblast proliferation and survival in idiopathic pulmonary fibrosis
por: Habiel, David M., et al.
Publicado: (2014)

Epigenetic Changes in Bone Marrow Progenitor Cells Influence the Inflammatory Phenotype and Alter Wound Healing in Type 2 Diabetes
por: Gallagher, Katherine A., et al.
Publicado: (2015)

Interleukin-33 contributes to both M1 and M2 chemokine marker expression in human macrophages
por: Joshi, Amrita D, et al.
Publicado: (2010)

Differences in H3K4me3 and chromatin accessibility contribute to altered T‐cell receptor signaling in neonatal naïve CD4 T cells
por: Bermick, Jennifer R, et al.
Publicado: (2022)

Lymphocyte trafficking and chemokine receptors during pulmonary disease
por: Lukacs, Nicholas W., et al.
Publicado: (2006)

Deficient repair response of IPF fibroblasts in a co-culture model of epithelial injury and repair
por: Prasad, Sony, et al.
Publicado: (2014)

Bilateral Avascular Necrosis of Hip: An Oddity in Endogenous Hypercortisolemia
por: Joseph, Aneez, et al.
Publicado: (2022)

Jagged-1 Reduces Th2 Inflammation and Memory Cell Expansion in Allergic Airway Disease
por: Kimura, Soichiro, et al.
Publicado: (2023)

HMGB1 Mediates Endogenous TLR2 Activation and Brain Tumor Regression
por: Curtin, James F, et al.
Publicado: (2009)

ST2/IL-33 signaling promotes malignant development of experimental squamous cell carcinoma by decreasing NK cells cytotoxicity and modulating the intratumoral cell infiltrate
por: Amôr, Nádia Ghinelli, et al.
Publicado: (2018)

T regulatory cells and attenuated bleomycin-induced fibrosis in lungs of CCR7(-/- )mice
por: Trujillo, Glenda, et al.
Publicado: (2010)

Aberrant innate immune sensing leads to the rapid progression of idiopathic pulmonary fibrosis
por: Hogaboam, Cory M, et al.
Publicado: (2012)

B Cell Antigen Presentation Promotes Th2 Responses and Immunopathology during Chronic Allergic Lung Disease
por: Lindell, Dennis M., et al.
Publicado: (2008)

Transcriptomic Analysis and C-Terminal Epitope Tagging Reveal Differential Processing and Signaling of Endogenous TLR3 and TLR7
por: Chen, Chiung-Ya, et al.
Publicado: (2021)

Role of CC chemokine CCL6/C10 as a monocyte chemoattractant in a murine acute peritonitis.
por: LaFleur, Andrew M, et al.
Publicado: (2004)

Central Nervous System-Endogenous TLR7 and TLR9 Induce Different Immune Responses and Effects on Experimental Autoimmune Encephalomyelitis
por: Dieu, Ruthe Storgaard, et al.
Publicado: (2021)

Protocol for using fluorescent sensors targeted to endogenous proteins (FluoSTEPs) to measure microdomain-specific signaling events
por: Zhang, Jason Z., et al.
Publicado: (2021)

Leptin Is an Endogenous Protective Protein against the Toxicity Exerted by Tumor Necrosis Factor
por: Takahashi, Nozomi, et al.
Publicado: (1999)

Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1
Publicado: (1986)

Endogenously produced catecholamines improve the regulatory function of TLR9-activated B cells
por: Honke, Nadine, et al.
Publicado: (2022)

Materials Characterization: Graphite-based and Cu-OFE Samples
por: Cavassani, Isadora Balbino
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_nmq9i393sjou4hauan3o2f7u7f