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Regional CNS responses to IFN-γ determine lesion localization patterns during EAE pathogenesis

The localization of inflammatory foci within the cerebellum is correlated to severe clinical outcomes in multiple sclerosis (MS). Previous studies of experimental autoimmune encephalomyelitis (EAE), a model of MS, revealed distinct clinical outcomes correlated with the capacity of the animal to prod...

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Detalles Bibliográficos
Autores principales: Lees, Jason R., Golumbek, Paul T., Sim, Julia, Dorsey, Denise, Russell, John H.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2571937/
https://www.ncbi.nlm.nih.gov/pubmed/18852291
http://dx.doi.org/10.1084/jem.20080155