CXCL12 (SDF-1α) suppresses ongoing experimental autoimmune encephalomyelitis by selecting antigen-specific regulatory T cells

Experimental autoimmune encephalomyelitis (EAE) is a T cell–mediated autoimmune disease of the central nervous system induced by antigen-specific effector Th17 and Th1 cells. We show that a key chemokine, CXCL12 (stromal cell–derived factor 1α), redirects the polarization of effector Th1 cells into...

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Detalles Bibliográficos
Autores principales: Meiron, Moran, Zohar, Yaniv, Anunu, Rachel, Wildbaum, Gizi, Karin, Nathan
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2571938/
https://www.ncbi.nlm.nih.gov/pubmed/18852294
http://dx.doi.org/10.1084/jem.20080730

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2571938/
https://www.ncbi.nlm.nih.gov/pubmed/18852294
http://dx.doi.org/10.1084/jem.20080730

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