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The presence of a functional t-tubule network increases the sensitivity of RyR1 to agonists in skinned rat skeletal muscle fibres

Single mechanically skinned extensor digitorum longus (EDL) rat fibres were used as a model to study the influence of functional t-tubules on the properties of RyR1 in adult skeletal muscle. Fibres were superfused with solutions approximating to the intracellular milieu. Following skinning, the t-tu...

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Detalles Bibliográficos
Autores principales: Duke, Adrian M., Steele, Derek S.
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2571965/
https://www.ncbi.nlm.nih.gov/pubmed/19230144
http://dx.doi.org/10.1016/j.ceca.2008.02.006