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Measurements of the BK(Ca) Channel's High-Affinity Ca(2+) Binding Constants: Effects of Membrane Voltage

It has been established that the large conductance Ca(2+)-activated K(+) channel contains two types of high-affinity Ca(2+) binding sites, termed the Ca(2+) bowl and the RCK1 site. The affinities of these sites, and how they change as the channel opens, is still a subject of some debate. Previous es...

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Detalles Bibliográficos
Autores principales: Sweet, Tara-Beth, Cox, Daniel H.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2571968/
https://www.ncbi.nlm.nih.gov/pubmed/18955592
http://dx.doi.org/10.1085/jgp.200810094