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Properties of the Inner Pore Region of TRPV1 Channels Revealed by Block with Quaternary Ammoniums

The transient receptor potential vanilloid 1 (TRPV1) nonselective cationic channel is a polymodal receptor that activates in response to a wide variety of stimuli. To date, little structural information about this channel is available. Here, we used quaternary ammonium ions (QAs) of different sizes...

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Detalles Bibliográficos
Autores principales: Jara-Oseguera, Andrés, Llorente, Itzel, Rosenbaum, Tamara, Islas, León D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2571972/
https://www.ncbi.nlm.nih.gov/pubmed/18955595
http://dx.doi.org/10.1085/jgp.200810051