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The P2X(7) Receptor Channel Pore Dilates under Physiological Ion Conditions
Activation of the purinergic P2X(7) receptor leads to the rapid opening of an integral ion channel that is permeable to small cations. This is followed by a gradual increase in permeability to fluorescent dyes by integrating the actions of the pannexin-1 channel. Here, we show that during the prolon...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2571973/ https://www.ncbi.nlm.nih.gov/pubmed/18852304 http://dx.doi.org/10.1085/jgp.200810059 |