A Sterol-Regulatory Element Binding Protein Is Required for Cell Polarity, Hypoxia Adaptation, Azole Drug Resistance, and Virulence in Aspergillus fumigatus

At the site of microbial infections, the significant influx of immune effector cells and the necrosis of tissue by the invading pathogen generate hypoxic microenvironments in which both the pathogen and host cells must survive. Currently, whether hypoxia adaptation is an important virulence attribut...

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Detalles Bibliográficos
Autores principales: Willger, Sven D., Puttikamonkul, Srisombat, Kim, Kwang-Hyung, Burritt, James B., Grahl, Nora, Metzler, Laurel J., Barbuch, Robert, Bard, Martin, Lawrence, Christopher B., Cramer, Robert A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2572145/
https://www.ncbi.nlm.nih.gov/pubmed/18989462
http://dx.doi.org/10.1371/journal.ppat.1000200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2572145/
https://www.ncbi.nlm.nih.gov/pubmed/18989462
http://dx.doi.org/10.1371/journal.ppat.1000200

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