Necrotic neurons enhance microglial neurotoxicity through induction of glutaminase by a MyD88-dependent pathway

BACKGROUND: Microglia are macrophage-like cells that constantly sense the microenvironment within the central nervous system (CNS). In the event of neuronal stress or injury, microglial cells rapidly react and change their phenotype. This response may lead to a deleterious type of microglial activat...

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Detalles Bibliográficos
Autores principales: Pais, Teresa F, Figueiredo, Catarina, Peixoto, Rui, Braz, Maria H, Chatterjee, Sukalyan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2572162/
https://www.ncbi.nlm.nih.gov/pubmed/18844999
http://dx.doi.org/10.1186/1742-2094-5-43

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2572162/
https://www.ncbi.nlm.nih.gov/pubmed/18844999
http://dx.doi.org/10.1186/1742-2094-5-43

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