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Lentivirus-mediated RNAi silencing targeting ABCC2 increasing the sensitivity of a human nasopharyngeal carcinoma cell line against cisplatin

BACKGROUND: High resistance to drug is taken as a characteristic of human tumors, which is usually mediated by multidrug resistance-associated genes. ABCC2, an ATP-binding cassette multidrug resistance transporter, is found to be expressed in a variety of human cancers. In this study the effect of a...

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Detalles Bibliográficos
Autores principales: Xie, Si Ming, Fang, Wei Yi, Liu, Zhen, Wang, Shuang Xi, Li, Xin, Liu, Teng Fei, Xie, Wei Bing, Yao, Kai Tai
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2572589/
https://www.ncbi.nlm.nih.gov/pubmed/18834541
http://dx.doi.org/10.1186/1479-5876-6-55