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Functional identification of NR2 subunits contributing to NMDA receptors on substance P receptor-expressing dorsal horn neurons

NMDA receptors are important elements in pain signaling in the spinal cord dorsal horn. They are heterotetramers typically composed of two NR1 and two of four NR2 subunits: NR2A-2D. Mice lacking specific NR2 subunits show deficits in pain transmission yet subunit location in the spinal cord remains...

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Detalles Bibliográficos
Autores principales: Tong, Chi-Kun, Kaftan, Edward J, MacDermott, Amy B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2572590/
https://www.ncbi.nlm.nih.gov/pubmed/18847474
http://dx.doi.org/10.1186/1744-8069-4-44