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Functional identification of NR2 subunits contributing to NMDA receptors on substance P receptor-expressing dorsal horn neurons
NMDA receptors are important elements in pain signaling in the spinal cord dorsal horn. They are heterotetramers typically composed of two NR1 and two of four NR2 subunits: NR2A-2D. Mice lacking specific NR2 subunits show deficits in pain transmission yet subunit location in the spinal cord remains...
Autores principales: | Tong, Chi-Kun, Kaftan, Edward J, MacDermott, Amy B |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2572590/ https://www.ncbi.nlm.nih.gov/pubmed/18847474 http://dx.doi.org/10.1186/1744-8069-4-44 |
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